Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNC001434

Drug Information
NameThiolactomycin
IndicationMalaria
[ICD9: 084   ICD10: B50-B54]
Experimental    
Not AvailableExperimental    
Structure

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InChI1S/C11H14O2S/c1-5-7(2)6-11(4)9(12)8(3)10(13)14-11/h5-6,13H,1H2,2-
4H3/b7-6+/t11-/m1/s1
InChIKeyHGCGJTZCWZFGBT-XUIVZRPNSA-N
Canonical SMILESCC1=C(SC(C1=O)(C)C=C(C)C=C)O    
Isomeric SMILESCC1=C(S[C@](C1=O)(C)/C=C(\C)/C=C)O
CAS NumberCAS 82079-32-1
PubChem Compound IDCID 445629.
PubChem Substance IDSID 13347.
Target3-oxoacyl-[acyl-carrier-protein] synthase IIBinder
Beta-ketoacyl-ACP synthase IBinder
Beta-ketoacyl-ACP synthase IIIBinder[1]
Enoyl-ACP reductaseInhibitor[2]
FabHBinder[3]
Ref 1The apicoplast as an antimalarial drug target. Drug Resist Updat. 2001 Jun;4(3):145-51. To Reference
Ref 2Novel molecular targets for antimalarial drug development. Chem Biol Drug Des. 2008 Apr;71(4):287-97. Epub 2008 Feb 22. To Reference
Ref 3Novel molecular targets for antimalarial chemotherapy. Int J Antimicrob Agents. 2007 Jul;30(1):4-10. Epub 2007 Mar 6. To Reference



 

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