Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC001435

Drug Information
[ICD9: 278   ICD10: E66]

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Canonical SMILESC1CCC(CC1)NC(=S)N2CCC(CC2)C3=CN=CN3    
CAS NumberCAS 106243-16-7
PubChem Compound IDCID 3035905.
PubChem Substance IDSID 705782.
TargetHistamine H3 receptorAntagonist[1][2]
Histamine H4 receptorAntagonist[3][4][1]
Ref 1The histamine H3 receptor: from gene cloning to H3 receptor drugs. Nat Rev Drug Discov. 2005 Feb;4(2):107-20. To Reference
Ref 2Combined histamine H1 and H3 receptor blockade produces nasal decongestion in an experimental model of nasal congestion. Am J Rhinol. 1999 Sep-Oct;13(5):391-9. To Reference
Ref 3Role of histamine in short- and long-term effects of methamphetamine on the developing mouse brain. J Neurochem. 2008 Nov;107(4):976-86. Epub 2008 Sep 11. To Reference
Ref 4Role of histamine H3 and H4 receptors in mechanical hyperalgesia following peripheral nerve injury. Neuroimmunomodulation. 2007;14(6):317-25. Epub 2008 Apr 10. To Reference


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