Therapeutic Targets Database
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TTD Drug ID: DNC001481

Drug Information
NameU50,488H
IndicationNot AvailableExperimental    
Structure

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InChI1S/C19H26Cl2N2O.C4H4O4/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17
-6-2-3-7-18(17)23-10-4-5-11-23;5-3(6)1-2-4(7)8/h8-9,12,17-18H,2-7
,10-11,13H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t17-,18-;/m1./s1
InChIKeyAVTJBFQWEHLNKK-JQUKZVPISA-N
Canonical SMILESCN(C1CCCCC1N2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl.C(=CC(=O)O)C(=O)O    
Isomeric SMILESCN([C@@H]1CCCC[C@H]1N2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl.C(=C\C(=O)O)\C(=O)
O
CAS NumberCAS 83913-06-8
PubChem Compound IDCID 56657849.
TargetKappa-type opioid receptorAgonist[1][2]
Ref 1The selective kappa-opioid receptor agonist U50,488H attenuates voluntary ethanol intake in the rat. Behav Brain Res. 2001 May;120(2):137-46. To Reference
Ref 2Effects of kappa- and mu-opioid receptor agonists on Ca2+ channels in neuroblastoma cells: involvement of the orphan opioid receptor. Eur J Pharmacol. 1999 Aug 27;379(2-3):191-8. To Reference



 

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