TTD Drug ID: DNC002879

Drug Information
Name	Piclamilast
Indication	Not Available			Experimental
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
InChI	1S/C18H18Cl2N2O3/c1-24-15-7-6-11(8-16(15)25-12-4-2-3-5-12)18(23)2 2-17-13(19)9-21-10-14(17)20/h6-10,12H,2-5H2,1H3,(H,21,22,23)
InChIKey	RRRUXBQSQLKHEL-UHFFFAOYSA-N
Canonical SMILES	COC1=C(C=C(C=C1)C(=O)NC2=C(C=NC=C2Cl)Cl)OC3CCCC3
CAS Number	CAS 144035-83-6
PubChem Compound ID	CID 154575.
Target	cAMP-specific 3',5'-cyclic phosphodiesterase 4A			Inhibitor	[1]
	cAMP-specific 3',5'-cyclic phosphodiesterase 4B			Inhibitor	[1]
	cAMP-specific 3',5'-cyclic phosphodiesterase 4D			Inhibitor	[1]
Ref 1	Beeh KM, Beier J, Lerch C, Schulz AK, Buhl R: Effects of piclamilast, a selective phosphodiesterase-4 inhibitor, on oxidative burst of sputum cells from mild asthmatics and stable COPD patients. Lung. 2004;182(6):369-77. To Reference

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