Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNC002879

Drug Information
NamePiclamilast
IndicationNot AvailableExperimental    
Structure

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InChI1S/C18H18Cl2N2O3/c1-24-15-7-6-11(8-16(15)25-12-4-2-3-5-12)18(23)2
2-17-13(19)9-21-10-14(17)20/h6-10,12H,2-5H2,1H3,(H,21,22,23)
InChIKeyRRRUXBQSQLKHEL-UHFFFAOYSA-N
Canonical SMILESCOC1=C(C=C(C=C1)C(=O)NC2=C(C=NC=C2Cl)Cl)OC3CCCC3    
CAS NumberCAS 144035-83-6
PubChem Compound IDCID 154575.
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4AInhibitor[1]
cAMP-specific 3',5'-cyclic phosphodiesterase 4BInhibitor[1]
cAMP-specific 3',5'-cyclic phosphodiesterase 4DInhibitor[1]
Ref 1Beeh KM, Beier J, Lerch C, Schulz AK, Buhl R: Effects of piclamilast, a selective phosphodiesterase-4 inhibitor, on oxidative burst of sputum cells from mild asthmatics and stable COPD patients. Lung. 2004;182(6):369-77. To Reference



 

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