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TTD Drug ID:
DNC002879
Drug
Information |
Name | Piclamilast | Indication | Not Available | Experimental | Structure |
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Click to save drug structure in 2D MOL format
| InChI | 1S/C18H18Cl2N2O3/c1-24-15-7-6-11(8-16(15)25-12-4-2-3-5-12)18(23)2 2-17-13(19)9-21-10-14(17)20/h6-10,12H,2-5H2,1H3,(H,21,22,23) | InChIKey | RRRUXBQSQLKHEL-UHFFFAOYSA-N | Canonical SMILES | COC1=C(C=C(C=C1)C(=O)NC2=C(C=NC=C2Cl)Cl)OC3CCCC3 | CAS Number | CAS 144035-83-6 | PubChem Compound ID | CID 154575. | Target | cAMP-specific 3',5'-cyclic phosphodiesterase 4A |  | Inhibitor | [1] | cAMP-specific 3',5'-cyclic phosphodiesterase 4B |  | Inhibitor | [1] | cAMP-specific 3',5'-cyclic phosphodiesterase 4D |  | Inhibitor | [1] | Ref 1 | Beeh KM, Beier J, Lerch C, Schulz AK, Buhl R: Effects of piclamilast, a selective phosphodiesterase-4 inhibitor, on oxidative burst of sputum cells from mild asthmatics and stable COPD patients. Lung. 2004;182(6):369-77. To Reference |
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