Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC003505

Drug Information
IndicationNot AvailableExperimental    

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Canonical SMILESCC1=C(C=CC(=C1)C2=NOC(=N2)C)C3=CC=C(C=C3)C(=O)NC4=CC(=C(C=C4)OC)N5CCN
TargetSerotonin 1a (5-HT1a) receptorInhibitor[1]
Serotonin 1b (5-HT1b) receptorInhibitor[2]
Serotonin 1d (5-HT1d) receptorInhibitor[2]
Serotonin 2a (5-HT2a) receptorInhibitor[2]
Serotonin 2c (5-HT2c) receptorInhibitor[2]
Ref 1J Med Chem. 2000 Feb 10;43(3):517-25.New selective and potent 5-HT(1B/1D) antagonists: chemistry and pharmacological evaluation of N-piperazinylphenyl biphenylcarboxamides and biphenylsulfonamides. To Reference
Ref 2Bioorg Med Chem Lett. 2005 Nov 1;15(21):4786-9.Synthesis of potent and selective serotonin 5-HT1B receptor ligands. To Reference


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