Therapeutic Targets Database
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TTD Drug ID: DNC003528

Drug Information
NameSCH-44342
IndicationNot AvailableExperimental    
Structure

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InChI1S/C26H24ClN3O/c27-22-5-6-23-21(17-22)4-3-20-2-1-11-29-26(20)25(2
3)19-9-14-30(15-10-19)24(31)16-18-7-12-28-13-8-18/h1-2,5-8,11-13,
17H,3-4,9-10,14-16H2
InChIKeyKIFXOXSGYMUANJ-UHFFFAOYSA-N
Canonical SMILESC1CC2=C(C=CC(=C2)Cl)C(=C3CCN(CC3)C(=O)CC4=CC=NC=C4)C5=C1C=CC=N5    
TargetProtein farnesyltransferase beta subunitInhibitor[1]
Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunitInhibitor[2]
Ref 1J Med Chem. 1997 Sep 12;40(19):2971-90.Ras farnesyltransferase: a new therapeutic target. To Reference
Ref 2J Med Chem. 1999 Jun 17;42(12):2125-35.Tricyclic farnesyl protein transferase inhibitors: crystallographic and calorimetric studies of structure-activity relationships. To Reference



 

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