Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC003528

Drug Information
IndicationNot AvailableExperimental    

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Canonical SMILESC1CC2=C(C=CC(=C2)Cl)C(=C3CCN(CC3)C(=O)CC4=CC=NC=C4)C5=C1C=CC=N5    
TargetProtein farnesyltransferase beta subunitInhibitor[1]
Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunitInhibitor[2]
Ref 1J Med Chem. 1997 Sep 12;40(19):2971-90.Ras farnesyltransferase: a new therapeutic target. To Reference
Ref 2J Med Chem. 1999 Jun 17;42(12):2125-35.Tricyclic farnesyl protein transferase inhibitors: crystallographic and calorimetric studies of structure-activity relationships. To Reference


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