Therapeutic Targets Database
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TTD Drug ID: DNC003584

Drug Information
NameCHLOROPHENYLPIPERAZINE
SynonymsCHLOROPHENYLPIPERAZINE
IndicationNot AvailableExperimental    
Structure

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TargetSerotonin 1a (5-HT1a) receptorInhibitor[1]
Serotonin 1d (5-HT1d) receptorInhibitor[1]
Serotonin 2a (5-HT2a) receptorInhibitor[2]
Serotonin 2b (5-HT2b) receptorInhibitor[2]
Serotonin 2c (5-HT2c) receptorInhibitor[2]
Serotonin 6 (5-HT6) receptorInhibitor[3]
Ref 1J Med Chem. 1989 May;32(5):1052-6.Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy. To Reference
Ref 2Bioorg Med Chem Lett. 2010 Feb 1;20(3):1128-33. Epub 2009 Dec 6.Tricyclic dihydroquinazolinones as novel 5-HT2C selective and orally efficacious anti-obesity agents. To Reference
Ref 3J Med Chem. 2003 Jul 3;46(14):2795-812.Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7). To Reference



 

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