Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNC003657

Drug Information
NameSB-271046
IndicationNot AvailableExperimental    
Structure

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InChI1S/C20H22ClN3O3S2.ClH/c1-13-16-11-14(21)3-6-19(16)28-20(13)29(25,
26)23-15-4-5-18(27-2)17(12-15)24-9-7-22-8-10-24;/h3-6,11-12,22-23
H,7-10H2,1-2H3;1H
InChIKeyRMXZRJYGJMSDQK-UHFFFAOYSA-N
Canonical SMILESCC1=C(SC2=C1C=C(C=C2)Cl)S(=O)(=O)NC3=CC(=C(C=C3)OC)N4CCNCC4.Cl    
TargetDopamine D1 receptorInhibitor[1]
Dopamine D2 receptorInhibitor[1]
Dopamine D3 receptorInhibitor[1]
Dopamine D4 receptorInhibitor[1]
Serotonin 1a (5-HT1a) receptorInhibitor[1]
Serotonin 2a (5-HT2a) receptorInhibitor[1]
Serotonin 2c (5-HT2c) receptorInhibitor[1]
Serotonin 6 (5-HT6) receptorInhibitor[2]
Serotonin 7 (5-HT7) receptorInhibitor[1]
Ref 1Bioorg Med Chem Lett. 2008 Jan 15;18(2):738-43. Epub 2007 Nov 17.Discovery of 3-aryl-3-methyl-1H-quinoline-2,4-diones as a new class of selective 5-HT6 receptor antagonists. To Reference
Ref 2Bioorg Med Chem Lett. 2009 May 1;19(9):2409-12. Epub 2009 Mar 25.Synthesis and SAR of tolylamine 5-HT6 antagonists. To Reference



 

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