TTD Drug ID: DNC003673

Drug Information
Name	PSAMMAPLIN A
Synonyms	PSAMMAPLIN A
Indication	Not Available			Experimental
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
InChI	1S/C22H24Br2N4O6S2/c23-15-9-13(1-3-19(15)29)11-17(27-33)21(31)25- 5-7-35-36-8-6-26-22(32)18(28-34)12-14-2-4-20(30)16(24)10-14/h1-4, 9-10,29-30,33-34H,5-8,11-12H2,(H,25,31)(H,26,32)/b27-17-,28-18-
InChIKey	LMAFSGDNHVBIHU-HJTNQMAYSA-N
Canonical SMILES	C1=CC(=C(C=C1CC(=NO)C(=O)NCCSSCCNC(=O)C(=NO)CC2=CC(=C(C=C2)O)Br)Br)O
Isomeric SMILES	C1=CC(=C(C=C1C/C(=N/O)/C(=O)NCCSSCCNC(=O)/C(=N\O)/CC2=CC(=C(C=C2)O)Br) Br)O
Target	Histone deacetylase 1			Inhibitor	[1]
	Histone deacetylase 10			Inhibitor	[1]
	Histone deacetylase 2			Inhibitor	[1]
	Histone deacetylase 4			Inhibitor	[1]
	Histone deacetylase 6			Inhibitor	[1]
	Histone deacetylase 7			Inhibitor	[1]
	Histone deacetylase 8			Inhibitor	[1]
	UDP-glucose 4-epimerase			Inhibitor	[2]
Ref 1	J Med Chem. 2003 Nov 20;46(24):5097-116.Histone deacetylase inhibitors. To Reference
Ref 2	Bioorg Med Chem Lett. 2006 Nov 15;16(22):5744-7. Epub 2006 Sep 7.Identification of novel inhibitors of UDP-Glc 4'-epimerase, a validated drug target for african sleeping sickness. To Reference

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