Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC003790

Drug Information
IndicationNot AvailableExperimental    

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
Canonical SMILESC1=C(NC(=C1Br)Br)C(=O)NCC=CC2=CN=C(N2)N    
Isomeric SMILESC1=C(NC(=C1Br)Br)C(=O)NC/C=C/C2=CN=C(N2)N
TargetDual specificity mitogen-activated protein kinase kinase 1Inhibitor[1]
Enoyl-acyl-carrier protein reductase Inhibitor[2]
Ref 1J Med Chem. 2002 Jan 17;45(2):529-32.Aldisine alkaloids from the Philippine sponge Stylissa massa are potent inhibitors of mitogen-activated protein kinase kinase-1 (MEK-1). To Reference
Ref 2Bioorg Med Chem. 2007 Nov 1;15(21):6834-45. Epub 2007 Aug 22.Marine natural products from the Turkish sponge Agelas oroides that inhibit the enoyl reductases from Plasmodium falciparum, Mycobacterium tuberculosis and Escherichia coli. To Reference


Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.

Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543