Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC003791

Drug Information
IndicationNot AvailableExperimental    

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
Canonical SMILESCOC1=CC=CC(=C1N)C2=CC(=O)C3=CC=CC=C3O2    
TargetDual specificity mitogen-activated protein kinase kinase 1Inhibitor[1]
Glycogen synthase kinase-3 betaInhibitor[2]
MAP kinase ERK2Inhibitor[2]
MAP kinase p38 alphaInhibitor[2]
MAP kinase p38 betaInhibitor[2]
MAP kinase p38 gammaInhibitor[2]
Protein kinase C alpha Inhibitor[2]
Rho-associated protein kinase 2Inhibitor[2]
Ribosomal protein S6 kinase alpha 5Inhibitor[2]
Serine/threonine-protein kinase AKTInhibitor[2]
Serine/threonine-protein kinase Chk1 Inhibitor[2]
Serine/threonine-protein kinase RAFInhibitor[1]
Serine/threonine-protein kinase Sgk1Inhibitor[2]
Tyrosine-protein kinase LCKInhibitor[2]
c-Jun N-terminal kinase 1Inhibitor[2]
Ref 1J Med Chem. 2002 Jan 17;45(2):529-32.Aldisine alkaloids from the Philippine sponge Stylissa massa are potent inhibitors of mitogen-activated protein kinase kinase-1 (MEK-1). To Reference
Ref 2Biochem J. 2000 Oct 1;351(Pt 1):95-105.Specificity and mechanism of action of some commonly used protein kinase inhibitors. To Reference


Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.

Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543