Therapeutic Targets Database
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TTD Drug ID: DNC003899

Drug Information
NameMK-10
IndicationNot AvailableExperimental    
Structure

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InChI1S/C41H55N11O7/c42-36(55)29-14-6-7-19-45-34(53)17-18-35(54)52-21-
9-16-33(52)40(59)51-31(22-25-10-2-1-3-11-25)38(57)49-30(15-8-20-4
6-41(43)44)37(56)50-32(39(58)48-29)23-26-24-47-28-13-5-4-12-27(26
)28/h1-5,10-13,24,29-33,47H,6-9,14-23H2,(H2,42,55)(H,45,53)(H,48,
58)(H,49,57)(H,50,56)(H,51,59)(H4,43,44,46)/t29-,30+,31-,32-,33+/
m0/s1
InChIKeyRSZGGZUMSYSTES-HJCKZFGESA-N
Canonical SMILESC1CCNC(=O)CCC(=O)N2CCCC2C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C1)C(=O)N)CC3=
CNC4=CC=CC=C43)CCCN=C(N)N)CC5=CC=CC=C5    
Isomeric SMILESC1CCNC(=O)CCC(=O)N2CCC[C@@H]2C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N
[C@@H](C1)C(=O)N)CC3=CNC4=CC=CC=C43)CCCN=C(N)N)CC5=CC=CC=C5
TargetMelanocortin receptor 3Inhibitor[1]
Melanocortin receptor 4Inhibitor[1]
Melanocortin receptor 5Inhibitor[1]
Ref 1J Med Chem. 2002 Jun 6;45(12):2644-50.Novel cyclic templates of alpha-MSH give highly selective and potent antagonists/agonists for human melanocortin-3/4 receptors. To Reference



 

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