Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNC004255

Drug Information
NamePD-168393
IndicationNot AvailableExperimental    
Structure

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InChI1S/C17H13BrN4O/c1-2-16(23)21-13-6-7-15-14(9-13)17(20-10-19-15)22-
12-5-3-4-11(18)8-12/h2-10H,1H2,(H,21,23)(H,19,20,22)
InChIKeyHTUBKQUPEREOGA-UHFFFAOYSA-N
Canonical SMILESC=CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=CC=C3)Br    
TargetEpidermal growth factor receptor erbB1Inhibitor[1]
Receptor protein-tyrosine kinase erbB-2Inhibitor[2]
Ref 1Nat Chem Biol. 2007 Apr;3(4):229-38. Epub 2007 Mar 4.Structure-guided development of affinity probes for tyrosine kinases using chemical genetics. To Reference
Ref 2J Med Chem. 1999 May 20;42(10):1803-15.Tyrosine kinase inhibitors. 15. 4-(Phenylamino)quinazoline and 4-(phenylamino)pyrido[d]pyrimidine acrylamides as irreversible inhibitors of the ATP binding site of the epidermal growth factor receptor. To Reference



 

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National University of Singapore, Singapore


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