Therapeutic Targets Database
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TTD Drug ID: DNC004399

Drug Information
NameNSC-19028
IndicationNot AvailableExperimental    
Structure

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InChI1S/C15H10O2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h
1-10H
InChIKeyVHBFFQKBGNRLFZ-UHFFFAOYSA-N
Canonical SMILESC1=CC=C(C=C1)C2=CC(=O)C3=CC=CC=C3O2    
TargetAdenosine A3 receptorInhibitor[1]
Androgen ReceptorInhibitor[2]
Cytochrome P450 19A1Inhibitor[3]
GABA receptor alpha-1 subunitInhibitor[4]
GABA receptor alpha-2 subunitInhibitor[5]
Ref 1J Med Chem. 1996 Feb 2;39(3):781-8.Interactions of flavonoids and other phytochemicals with adenosine receptors. To Reference
Ref 2Bioorg Med Chem Lett. 2009 Aug 15;19(16):4706-10. Epub 2009 Jun 23.Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay. To Reference
Ref 3Bioorg Med Chem Lett. 2010 May 15;20(10):3050-64. Epub 2010 Apr 8.Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19). To Reference
Ref 4Bioorg. Med. Chem. Lett. 7(15):2003-2008 (1997) To Reference
Ref 5J Med Chem. 2002 Sep 12;45(19):4188-201.Refinement and evaluation of a pharmacophore model for flavone derivatives binding to the benzodiazepine site of the GABA(A) receptor. To Reference



 

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