Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC004406

Drug Information
IndicationNot AvailableExperimental    

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Canonical SMILESC1=CC=C2C(=C1)C(=CN2)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54    
TargetCyclin-dependent kinase 1Inhibitor[1]
G2/mitotic-specific cyclin B1Inhibitor[1]
MAP kinase ERK2Inhibitor[2]
MAP kinase p38 alphaInhibitor[2]
MAP kinase p38 betaInhibitor[2]
MAP kinase p38 gammaInhibitor[2]
NAD-dependent deacetylase sirtuin 1Inhibitor[3]
Protein kinase C alpha Inhibitor[4]
Protein kinase C betaInhibitor[4]
Protein kinase C deltaInhibitor[4]
Protein kinase C epsilonInhibitor[4]
Protein kinase C epsilonInhibitor[5]
Protein kinase C gammaInhibitor[4]
Protein kinase C thetaInhibitor[4]
Protein kinase C zetaInhibitor[4]
Rho-associated protein kinase 2Inhibitor[2]
Ribosomal protein S6 kinase alpha 5Inhibitor[2]
Serine/threonine-protein kinase AKTInhibitor[2]
Serine/threonine-protein kinase Chk1 Inhibitor[2]
Serine/threonine-protein kinase Sgk1Inhibitor[2]
Tyrosine-protein kinase LCKInhibitor[2]
c-Jun N-terminal kinase 1Inhibitor[2]
cAMP-dependent protein kinase alpha-catalytic subunitInhibitor[4]
Ref 1Bioorg Med Chem Lett. 1998 May 5;8(9):1019-22.Design of new inhibitors for cdc2 kinase based on a multiple pseudosubstrate structure. To Reference
Ref 2Biochem J. 2000 Oct 1;351(Pt 1):95-105.Specificity and mechanism of action of some commonly used protein kinase inhibitors. To Reference
Ref 3J Med Chem. 2006 Dec 14;49(25):7307-16.Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition. To Reference
Ref 4J Med Chem. 1992 Jan;35(1):177-84.Inhibitors of protein kinase C. 1. 2,3-Bisarylmaleimides. To Reference
Ref 5Bioorg Med Chem Lett. 2004 Oct 18;14(20):5171-4.Synthesis of anilino-monoindolylmaleimides as potent and selective PKCbeta inhibitors. To Reference


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