Therapeutic Targets Database
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TTD Drug ID: DNC004485

Drug Information
NameFADROZOLE HCL
SynonymsFADROZOLE HCL
IndicationNot AvailableExperimental    
Structure

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InChI1S/C14H13N3.ClH/c15-8-11-4-6-12(7-5-11)14-3-1-2-13-9-16-10-17(13)
14;/h4-7,9-10,14H,1-3H2;1H
InChIKeyUKCVAQGKEOJTSR-UHFFFAOYSA-N
Canonical SMILESC1CC(N2C=NC=C2C1)C3=CC=C(C=C3)C#N.Cl    
TargetCytochrome P450 11B1Inhibitor[1]
Cytochrome P450 19A1Inhibitor[2]
Ref 1J Med Chem. 1991 Feb;34(2):725-36.Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of aromatase for the treatment of estrogen-dependent disease. To Reference
Ref 2Bioorg Med Chem Lett. 2008 Aug 15;18(16):4713-5. Epub 2008 Jul 3.Synthesis of 6- or 4-functionalized indoles via a reductive cyclization approach and evaluation as aromatase inhibitors. To Reference



 

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