Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNC004618

Drug Information
NameFK-453
IndicationNot AvailableExperimental    
Structure

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InChI1S/C23H25N3O2/c27-17-14-19-10-4-6-15-25(19)22(28)13-12-20-21-11-5
-7-16-26(21)24-23(20)18-8-2-1-3-9-18/h1-3,5,7-9,11-13,16,19,27H,4
,6,10,14-15,17H2/b13-12+/t19-/m1/s1
InChIKeyOPLOPFHUHFGKMJ-JXOMPUQVSA-N
Canonical SMILESC1CCN(C(C1)CCO)C(=O)C=CC2=C3C=CC=CN3N=C2C4=CC=CC=C4    
Isomeric SMILESC1CCN([C@H](C1)CCO)C(=O)/C=C/C2=C3C=CC=CN3N=C2C4=CC=CC=C4
TargetAdenosine A1 receptorInhibitor[1]
Adenosine A2a receptorInhibitor[1]
Adenosine A2b receptorInhibitor[2]
Ref 1Bioorg Med Chem. 2010 Mar 15;18(6):2195-203. Epub 2010 Feb 4.2-Amino-5-benzoyl-4-phenylthiazoles: Development of potent and selective adenosine A1 receptor antagonists. To Reference
Ref 2J Med Chem. 2001 Jan 18;44(2):170-9.2-Alkynyl-8-aryl-9-methyladenines as novel adenosine receptor antagonists: their synthesis and structure-activity relationships toward hepatic glucose production induced via agonism of the A(2B) receptor. To Reference



 

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