Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNC004667

Drug Information
NameCarzenide;Para-Carboxybenzenesulfonamide (Weak Carbonic Anhydrase Inhibitor)
IndicationNot AvailableExperimental    
Structure

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InChI1S/C7H7NO4S/c8-13(11,12)6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)(H2,8,
11,12)
InChIKeyUCAGLBKTLXCODC-UHFFFAOYSA-N
Canonical SMILESC1=CC(=CC=C1C(=O)O)S(=O)(=O)N    
TargetCarbonic anhydrase 15Inhibitor[1]
Carbonic anhydrase IInhibitor[2]
Carbonic anhydrase IIInhibitor[3]
Carbonic anhydrase IXInhibitor[1]
Carbonic anhydrase VIInhibitor[1]
Carbonic anhydrase XIIInhibitor[4]
Carbonic anhydrase XIVInhibitor[5]
Ref 1J Med Chem. 2009 Feb 12;52(3):646-54.Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. To Reference
Ref 2Nat Chem Biol. 2009 May;5(5):341-3. Epub 2009 Mar 29.Ligand-directed tosyl chemistry for protein labeling in vivo. To Reference
Ref 3Bioorg Med Chem Lett. 2005 Dec 15;15(24):5429-33. Epub 2005 Oct 6.Synthesis and structure-activity relationships of novel benzene sulfonamides with potent binding affinity for bovine carbonic anhydrase II. To Reference
Ref 4Bioorg Med Chem Lett. 2005 Feb 15;15(4):963-9.Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs? To Reference
Ref 5Bioorg Med Chem Lett. 2005 Sep 1;15(17):3828-33.Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides. To Reference



 

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