Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNC004886

Drug Information
NameMAFENIDE
SynonymsMAFENIDE
IndicationNot AvailableExperimental    
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C7H10N2O2S/c8-5-6-1-3-7(4-2-6)12(9,10)11/h1-4H,5,8H2,(H2,9,10,
11)
InChIKeyTYMRLRRVMHJFTF-UHFFFAOYSA-N
Canonical SMILESC1=CC(=CC=C1CN)S(=O)(=O)N    
CAS NumberCAS 138-39-6
SuperDrug ATC IDD06BA03
D06BA03
TargetCarbonic anhydrase 15Inhibitor[1]
Carbonic anhydrase IIInhibitor[2]
Carbonic anhydrase IVInhibitor[3]
Carbonic anhydrase IXInhibitor[2]
Carbonic anhydrase VIInhibitor[1]
Carbonic anhydrase XIIInhibitor[2]
Carbonic anhydrase XIVInhibitor[4]
Ref 1J Med Chem. 2009 Feb 12;52(3):646-54.Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV. To Reference
Ref 2J Med Chem. 2010 Apr 8;53(7):2913-26.Sulfonamide linked neoglycoconjugates--a new class of inhibitors for cancer-associated carbonic anhydrases. To Reference
Ref 3Bioorg Med Chem Lett. 2005 Feb 15;15(4):1149-54.Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides. To Reference
Ref 4Bioorg Med Chem Lett. 2005 Sep 1;15(17):3828-33.Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543