Therapeutic Targets Database
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TTD Drug ID: DNC005173

Drug Information
NameGW-328267
IndicationNot AvailableExperimental    
Structure

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InChI1S/C21H26N10O4/c1-2-31-28-18(27-29-31)16-14(33)15(34)20(35-16)30-
10-23-13-17(22)25-21(26-19(13)30)24-12(9-32)8-11-6-4-3-5-7-11/h3-
7,10,12,14-16,20,32-34H,2,8-9H2,1H3,(H3,22,24,25,26)/t12-,14-,15+
,16-,20+/m0/s1
InChIKeyFLBKPDIBGNWXMT-NIQZGXKPSA-N
Canonical SMILESCCN1N=C(N=N1)C2C(C(C(O2)N3C=NC4=C3N=C(N=C4N)NC(CC5=CC=CC=C5)CO)O)O    
Isomeric SMILESCCN1N=C(N=N1)[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C3N=C(N=C4N)N[C@@H]
(CC5=CC=CC=C5)CO)O)O
TargetAdenosine A1 receptorInhibitor[1]
Adenosine A2a receptorInhibitor[2]
Adenosine A2b receptorInhibitor[1]
Adenosine A3 receptorInhibitor[1]
Ref 1J Med Chem. 2004 Jul 29;47(16):4041-53.Synthesis and biological activity of new potential agonists for the human adenosine A2A receptor. To Reference
Ref 2Bioorg Med Chem Lett. 2010 Feb 1;20(3):1219-24. Epub 2009 Dec 1.Synthesis and evaluation of two series of 4'-aza-carbocyclic nucleosides as adenosine A2A receptor agonists. To Reference



 

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