Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC006613

Drug Information
IndicationNot AvailableExperimental    

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Canonical SMILESC1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O    
Target3-oxoacyl-acyl-carrier protein reductase Inhibitor[1]
Aldose reductaseInhibitor[2]
Androgen ReceptorInhibitor[3]
Arachidonate 15-lipoxygenaseInhibitor[4]
Arachidonate 5-lipoxygenaseInhibitor[4]
Cytochrome P450 1B1Inhibitor[5]
Estradiol 17-beta-dehydrogenase 1Inhibitor[6]
Glyoxalase IInhibitor[7]
Ref 1J Med Chem. 2006 Jun 1;49(11):3345-53.Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids. To Reference
Ref 2J Nat Prod. 2008 Apr;71(4):713-5. Epub 2008 Feb 26.Erigeroflavanone, a flavanone derivative from the flowers of Erigeron annuus with protein glycation and aldose reductase inhibitory activity. To Reference
Ref 3Bioorg Med Chem Lett. 2009 Aug 15;19(16):4706-10. Epub 2009 Jun 23.Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay. To Reference
Ref 4J Nat Prod. 2007 May;70(5):859-62. Epub 2007 Mar 23.Lipoxygenase inhibitory constituents of the fruits of noni (Morinda citrifolia) collected in Tahiti. To Reference
Ref 5Bioorg Med Chem. 2010 Sep 1;18(17):6310-5. Epub 2010 Jul 13.Selective inhibition of methoxyflavonoids on human CYP1B1 activity. To Reference
Ref 6J Med Chem. 2008 Jul 24;51(14):4188-99. Epub 2008 Jun 6.Discovery of nonsteroidal 17beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries. To Reference
Ref 7Bioorg Med Chem. 2008 Apr 1;16(7):3969-75. Epub 2008 Jan 24.Structure-activity relationship of human GLO I inhibitory natural flavonoids and their growth inhibitory effects. To Reference
Ref 8Bioorg Med Chem. 2009 Oct 1;17(19):6816-23. Epub 2009 Aug 21.Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities. To Reference


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