Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNC007460

Drug Information
NameTG-100435
IndicationNot AvailableExperimental    
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C26H25Cl2N5O/c1-17-15-18(24-21(27)5-4-6-22(24)28)16-23-25(17)3
0-26(32-31-23)29-19-7-9-20(10-8-19)34-14-13-33-11-2-3-12-33/h4-10
,15-16H,2-3,11-14H2,1H3,(H,29,30,32)
InChIKeyOTTCBLPTHPBEEX-UHFFFAOYSA-N
Canonical SMILESCC1=C2C(=CC(=C1)C3=C(C=CC=C3Cl)Cl)N=NC(=N2)NC4=CC=C(C=C4)OCCN5CCCC5    
TargetEphrin type-B receptor 4Inhibitor[1]
Fibroblast growth factor receptor 2Inhibitor[1]
Platelet-derived growth factor receptor betaInhibitor[1]
Tyrosine-protein kinase ABLInhibitor[1]
Tyrosine-protein kinase LCKInhibitor[1]
Tyrosine-protein kinase SRCInhibitor[1]
Tyrosine-protein kinase YESInhibitor[1]
Tyrosine-protein kinase receptor RETInhibitor[1]
Vascular endothelial growth factor receptor 2Inhibitor[1]
Ref 1Bioorg Med Chem Lett. 2007 Feb 1;17(3):602-8. Epub 2006 Nov 7.Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine--a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543