Therapeutic Targets Database
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TTD Drug ID: DNC008125

Drug Information
NameGT-1282;NIBR-1282
IndicationNot AvailableExperimental    
Structure

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InChI1S/C30H37N5O2/c1-23-11-19-34(37)24(2)28(23)29(36)32-20-14-30(3,15
-21-32)33-17-12-26(13-18-33)35(25-8-5-4-6-9-25)27-10-7-16-31-22-2
7/h4-11,16,19,22,26H,12-15,17-18,20-21H2,1-3H3
InChIKeyDDVVRHNNOPQPGB-UHFFFAOYSA-N
Canonical SMILESCC1=C(C(=[N+](C=C1)[O-])C)C(=O)N2CCC(CC2)(C)N3CCC(CC3)N(C4=CC=CC=C4)C5=
CN=CC=C5    
TargetC-C chemokine receptor type 5Inhibitor[1]
Ref 1Bioorg Med Chem Lett. 2008 Mar 15;18(6):2000-5. Epub 2008 Feb 2.Reduced cardiac side-effect potential by introduction of polar groups: discovery of NIBR-1282, an orally bioavailable CCR5 antagonist which is active in vivo. To Reference



 

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