TTD Drug ID: DNC008339

Drug Information
Name	JUGLONE
Synonyms	JUGLONE
Indication	Not Available			Experimental
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
InChI	1S/C10H6O3/c11-7-4-5-9(13)10-6(7)2-1-3-8(10)12/h1-5,12H
InChIKey	KQPYUDDGWXQXHS-UHFFFAOYSA-N
Canonical SMILES	C1=CC2=C(C(=O)C=CC2=O)C(=C1)O
Target	Arachidonate 5-lipoxygenase			Inhibitor	[1]
	Dual specificity phosphatase Cdc25B			Inhibitor	[2]
	Dual specificity protein phosphatase 1			Inhibitor	[2]
	Indoleamine 2,3-dioxygenase			Inhibitor	[3]
Ref 1	J Med Chem. 1997 Nov 7;40(23):3773-80.Simple analogues of anthralin: unusual specificity of structure and antiproliferative activity. To Reference
Ref 2	Bioorg Med Chem. 2009 Mar 15;17(6):2276-81. Epub 2008 Nov 8.Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases. To Reference
Ref 3	J Med Chem. 2008 Mar 27;51(6):1706-18. Epub 2008 Mar 5.Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors. To Reference

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