Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC008950

Drug Information
IndicationNot AvailableExperimental    

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TargetAMP-activated protein kinase, alpha-2 subunitInhibitor[1]
Glycogen synthase kinase-3 betaInhibitor[2]
Protein kinase C betaInhibitor[1]
Protein kinase C deltaInhibitor[1]
Protein kinase C epsilonInhibitor[1]
Protein kinase C etaInhibitor[1]
Protein kinase C thetaInhibitor[1]
Rho-associated protein kinase 1 Inhibitor[1]
Serine/threonine-protein kinase AKTInhibitor[1]
Serine/threonine-protein kinase AKT3Inhibitor[1]
cGMP-dependent protein kinase 1 betaInhibitor[1]
Ref 1J Med Chem. 2008 Sep 25;51(18):5663-79.Identification of 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a novel inhibitor of AKT kinase. To Reference
Ref 2Bioorg Med Chem Lett. 2009 Mar 1;19(5):1508-11. Epub 2009 Jan 9.Aminofurazans as potent inhibitors of AKT kinase. To Reference


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