Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC008993

Drug Information
IndicationNot AvailableExperimental    

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Canonical SMILESCOC1=CC2=C(C=C1)C3=C4C(=C5C6=CC=CC=C6N(C5=C3CC2)CCO)CNC4=O    
TargetMitogen-activated protein kinase kinase kinase 10Inhibitor[1]
Mitogen-activated protein kinase kinase kinase 11Inhibitor[1]
Mitogen-activated protein kinase kinase kinase 9Inhibitor[1]
Nerve growth factor receptor Trk-AInhibitor[1]
Tyrosine-protein kinase FYNInhibitor[1]
Tyrosine-protein kinase LCKInhibitor[1]
Vascular endothelial growth factor receptor 2Inhibitor[1]
Ref 1J Med Chem. 2008 Sep 25;51(18):5680-9. Epub 2008 Aug 21.Mixed-lineage kinase 1 and mixed-lineage kinase 3 subtype-selective dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: optimization, mixed-lineage kinase 1 crystallography, and oral in vivo activity in 1-methyl-4-phenyltetrahydropyridine models. To Reference


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