Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DNC009225

Drug Information
IndicationNot AvailableExperimental    

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Canonical SMILESCC(C1=CC=CC=C1)NC2=NC=CC(=C2)C3=C(N=C(N3C)C4CCNCC4)C5=CC(=CC=C5)C(F)(F)F    
Isomeric SMILESC[C@@H](C1=CC=CC=C1)NC2=NC=CC(=C2)C3=C(N=C(N3C)C4CCNCC4)C5=CC(=CC=C5)C
TargetSerine/threonine-protein kinase RAFInhibitor[1]
Ref 1J Med Chem. 2008 Jul 24;51(14):4122-49. Epub 2008 Jun 26.Design, synthesis, and biological evaluation of novel Tri- and tetrasubstituted imidazoles as highly potent and specific ATP-mimetic inhibitors of p38 MAP kinase: focus on optimized interactions with the enzyme's surface-exposed front region. To Reference


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