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TTD Drug ID:
DNC009404
Drug
Information |
Name | N-[5-(methylthio)-1,3,4-thiadiazol-2-yl]sulfamide | Indication | Not Available | Experimental | Structure |
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| InChI | 1S/C3H6N4O2S3/c1-10-3-6-5-2(11-3)7-12(4,8)9/h1H3,(H,5,7)(H2,4,8,9 ) | InChIKey | AJEMPSSJQSOJKR-UHFFFAOYSA-N | Canonical SMILES | CSC1=NN=C(S1)NS(=O)(=O)N | Target | Carbonic anhydrase I |  | Inhibitor | [1] | Carbonic anhydrase II |  | Inhibitor | [1] | Carbonic anhydrase IV |  | Inhibitor | [1] | Carbonic anhydrase VB |  | Inhibitor | [1] | Ref 1 | Bioorg Med Chem Lett. 2008 Dec 15;18(24):6332-5. Epub 2008 Nov 1.Carbonic anhydrase inhibitors: 2-substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV. To Reference |
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