Therapeutic Targets Database
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TTD Drug ID: DNC010492

Drug Information
Name1-(4-Bromobenzyl)-1H-imidazole
1-(4-bromobenzyl)-1H-imidazole
IndicationNot AvailableExperimental    
Structure

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InChI1S/C10H9BrN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2
InChIKeyMZJSYLIOMLCYIS-UHFFFAOYSA-N
Canonical SMILESC1=CC(=CC=C1CN2C=CN=C2)Br    
TargetCytochrome P450 11B1Inhibitor[1]
Cytochrome P450 17A1Inhibitor[2]
Ref 1J Med Chem. 2010 Feb 25;53(4):1712-25.Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). To Reference
Ref 2Bioorg Med Chem Lett. 2006 Sep 15;16(18):4752-6. Epub 2006 Jul 25.Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of 4-substituted phenyl alkyl imidazole-based inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)). To Reference



 

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