TTD Drug ID: DNC010627

Drug Information
Name	RO-320432
Synonyms	RO-320432
Indication	Not Available			Experimental
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
InChI	1S/C28H28N4O2/c1-30(2)15-17-12-13-32-22-11-7-5-9-19(22)24(23(32)1 4-17)26-25(27(33)29-28(26)34)20-16-31(3)21-10-6-4-8-18(20)21/h4-1 1,16-17H,12-15H2,1-3H3,(H,29,33,34)/t17-/m0/s1
InChIKey	FXGHOAZJQNLNFD-KRWDZBQOSA-N
Canonical SMILES	CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C5CC(CCN5C6=CC=CC=C64)CN(C)C
Isomeric SMILES	CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C5C[C@H](CCN5C6=CC=CC=C64)CN(C)C
Target	Glycogen synthase kinase-3 beta			Inhibitor	[1]
	Protein kinase C alpha			Inhibitor	[2]
	Protein kinase C beta			Inhibitor	[2]
	Protein kinase C delta			Inhibitor	[2]
	Protein kinase C epsilon			Inhibitor	[2]
	Protein kinase C gamma			Inhibitor	[2]
	Protein kinase C theta			Inhibitor	[2]
	Protein kinase C zeta			Inhibitor	[2]
Ref 1	Bioorg Med Chem Lett. 2010 Mar 1;20(5):1693-6. Epub 2010 Jan 25.Discovery of potent and bioavailable GSK-3beta inhibitors. To Reference
Ref 2	Bioorg. Med. Chem. Lett. 4(11):1303-1308 (1994) To Reference

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