Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNC011078

Drug Information
NameOctanedioic acid bis-hydroxyamide
Suberohydroxamic acid
IndicationNot AvailableExperimental    
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C8H16N2O4/c11-7(9-13)5-3-1-2-4-6-8(12)10-14/h13-14H,1-6H2,(H,9
,11)(H,10,12)
InChIKeyIDQPVOFTURLJPT-UHFFFAOYSA-N
Canonical SMILESC(CCCC(=O)NO)CCC(=O)NO    
TargetHistone deacetylase 1Inhibitor[1]
Histone deacetylase 2Inhibitor[1]
Histone deacetylase 4Inhibitor[1]
Histone deacetylase 5Inhibitor[2]
Histone deacetylase 6Inhibitor[1]
Histone deacetylase 8Inhibitor[2]
Ref 1J Med Chem. 2002 Jul 18;45(15):3296-309.Structure-activity relationships on phenylalanine-containing inhibitors of histone deacetylase: in vitro enzyme inhibition, induction of differentiation, and inhibition of proliferation in Friend leukemic cells. To Reference
Ref 2Nat Chem Biol. 2010 Mar;6(3):238-243. Epub 2010 Feb 7.Chemical phylogenetics of histone deacetylases. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543