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TTD Drug ID:
DNC011078
Drug
Information |
Name | Octanedioic acid bis-hydroxyamide | Suberohydroxamic acid | Indication | Not Available | Experimental | Structure |
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| InChI | 1S/C8H16N2O4/c11-7(9-13)5-3-1-2-4-6-8(12)10-14/h13-14H,1-6H2,(H,9 ,11)(H,10,12) | InChIKey | IDQPVOFTURLJPT-UHFFFAOYSA-N | Canonical SMILES | C(CCCC(=O)NO)CCC(=O)NO | Target | Histone deacetylase 1 |  | Inhibitor | [1] | Histone deacetylase 2 |  | Inhibitor | [1] | Histone deacetylase 4 |  | Inhibitor | [1] | Histone deacetylase 5 |  | Inhibitor | [2] | Histone deacetylase 6 |  | Inhibitor | [1] | Histone deacetylase 8 |  | Inhibitor | [2] | Ref 1 | J Med Chem. 2002 Jul 18;45(15):3296-309.Structure-activity relationships on phenylalanine-containing inhibitors of histone deacetylase: in vitro enzyme inhibition, induction of differentiation, and inhibition of proliferation in Friend leukemic cells. To Reference | Ref 2 | Nat Chem Biol. 2010 Mar;6(3):238-243. Epub 2010 Feb 7.Chemical phylogenetics of histone deacetylases. To Reference |
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