TTD Drug ID: DNC011188

Drug Information
Name	CI-1040;PD-18435;PD-184352
Indication	Not Available			Experimental
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
InChI	1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15 (16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24)
InChIKey	GFMMXOIFOQCCGU-UHFFFAOYSA-N
Canonical SMILES	C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl
Target	Glycogen synthase kinase-3 beta			Inhibitor	[1]
	MAP kinase ERK2			Inhibitor	[1]
	MAP kinase p38 alpha			Inhibitor	[1]
	MAP kinase p38 beta			Inhibitor	[1]
	MAP kinase p38 gamma			Inhibitor	[1]
	Protein kinase C alpha			Inhibitor	[1]
	Rho-associated protein kinase 2			Inhibitor	[1]
	Ribosomal protein S6 kinase alpha 5			Inhibitor	[1]
	Serine/threonine-protein kinase AKT			Inhibitor	[1]
	Serine/threonine-protein kinase Chk1			Inhibitor	[1]
	Serine/threonine-protein kinase Sgk1			Inhibitor	[1]
	Tyrosine-protein kinase LCK			Inhibitor	[1]
	c-Jun N-terminal kinase 1			Inhibitor	[1]
Ref 1	Biochem J. 2000 Oct 1;351(Pt 1):95-105.Specificity and mechanism of action of some commonly used protein kinase inhibitors. To Reference

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Professor in Department of Pharmacy
National University of Singapore, Singapore

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