TTD Drug ID: DNC011752

Drug Information
Name	RO-145974
Synonyms	RO-145974
Indication	Not Available			Experimental
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
InChI	1S/C17H17N3O3/c1-2-23-17(22)14-15-13-8-5-9-19(13)16(21)11-6-3-4-7 -12(11)20(15)10-18-14/h3-4,6-7,10,13H,2,5,8-9H2,1H3/t13-/m0/s1
InChIKey	VUSVWZBQTTWZGJ-ZDUSSCGKSA-N
Canonical SMILES	CCOC(=O)C1=C2C3CCCN3C(=O)C4=CC=CC=C4N2C=N1
Isomeric SMILES	CCOC(=O)C1=C2[C@@H]3CCCN3C(=O)C4=CC=CC=C4N2C=N1
Target	GABA receptor alpha-1 subunit			Inhibitor	[1]
	GABA receptor alpha-2 subunit			Inhibitor	[1]
	GABA receptor beta-2 subunit			Inhibitor	[1]
	GABA receptor gamma-2 subunit			Inhibitor	[1]
Ref 1	J Med Chem. 1993 Apr 16;36(8):1001-6.Synthesis and evaluation of imidazo[1,5-a][1,4]benzodiazepine esters with high affinities and selectivities at "diazepam-insensitive" benzodiazepine receptors. To Reference

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