|
|
TTD Drug ID:
DNC011752
Drug
Information |
Name | RO-145974 | Synonyms | RO-145974 | Indication | Not Available | Experimental | Structure |
Click to save drug structure in 3D MOL format
Click to save drug structure in 2D MOL format
| InChI | 1S/C17H17N3O3/c1-2-23-17(22)14-15-13-8-5-9-19(13)16(21)11-6-3-4-7 -12(11)20(15)10-18-14/h3-4,6-7,10,13H,2,5,8-9H2,1H3/t13-/m0/s1 | InChIKey | VUSVWZBQTTWZGJ-ZDUSSCGKSA-N | Canonical SMILES | CCOC(=O)C1=C2C3CCCN3C(=O)C4=CC=CC=C4N2C=N1 | Isomeric SMILES | CCOC(=O)C1=C2[C@@H]3CCCN3C(=O)C4=CC=CC=C4N2C=N1 | Target | GABA receptor alpha-1 subunit |  | Inhibitor | [1] | GABA receptor alpha-2 subunit |  | Inhibitor | [1] | GABA receptor beta-2 subunit |  | Inhibitor | [1] | GABA receptor gamma-2 subunit |  | Inhibitor | [1] | Ref 1 | J Med Chem. 1993 Apr 16;36(8):1001-6.Synthesis and evaluation of imidazo[1,5-a][1,4]benzodiazepine esters with high affinities and selectivities at "diazepam-insensitive" benzodiazepine receptors. To Reference |
Welcome
to sign our Guestbook.
If you
find any error in data or bug in web service, please kindly report it
to Dr.
Zhu.
Dr.
Chen Yuzong
Deputy Director of Center
for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore
All rights reserved.
|