Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNC011862

Drug Information
NameU-78875
SynonymsU-78875
IndicationNot AvailableExperimental    
Structure

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InChI1S/C18H17N5O2/c1-10(2)23-13-6-4-3-5-12(13)22-9-19-14(15(22)18(23)
24)16-20-17(25-21-16)11-7-8-11/h3-6,9-11H,7-8H2,1-2H3
InChIKeyZGEGOFCLSWVVKG-UHFFFAOYSA-N
Canonical SMILESCC(C)N1C2=CC=CC=C2N3C=NC(=C3C1=O)C4=NOC(=N4)C5CC5    
TargetGABA receptor alpha-1 subunitInhibitor[1]
GABA receptor beta-2 subunitInhibitor[2]
GABA receptor gamma-1 subunitInhibitor[1]
GABA receptor gamma-2 subunitInhibitor[3]
Ref 1J Med Chem. 1999 Apr 8;42(7):1123-44.Piperazine imidazo[1,5-a]quinoxaline ureas as high-affinity GABAA ligands of dual functionality. To Reference
Ref 2J Med Chem. 1996 Nov 8;39(23):4654-66.High-affinity alpha-aminobutyric acid A/benzodiazepine ligands: synthesis and structure-activity relationship studies of a new series of tetracyclic imidazoquinoxalines. To Reference
Ref 3J Med Chem. 1996 Sep 13;39(19):3820-36.3-Phenyl-substituted imidazo[1,5-alpha]quinoxalin-4-ones and imidazo[1,5-alpha]quinoxaline ureas that have high affinity at the GABAA/benzodiazepine receptor complex. To Reference



 

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