TTD Drug ID: DNC012464

Drug Information
Name	3-(4-Hydroxy-phenyl)-2,3-diphenyl-acrylonitrile
Indication	Not Available			Experimental
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
InChI	1S/C21H15NO/c22-15-20(16-7-3-1-4-8-16)21(17-9-5-2-6-10-17)18-11-1 3-19(23)14-12-18/h1-14,23H/b21-20+
InChIKey	ASWQVWZGOMLNRM-QZQOTICOSA-N
Canonical SMILES	C1=CC=C(C=C1)C(=C(C2=CC=CC=C2)C3=CC=C(C=C3)O)C#N
Isomeric SMILES	C1=CC=C(C=C1)/C(=C(\C2=CC=CC=C2)/C3=CC=C(C=C3)O)/C#N
Target	Protein kinase C alpha			Inhibitor	[1]
	Protein kinase C beta			Inhibitor	[1]
	Protein kinase C delta			Inhibitor	[1]
	Protein kinase C epsilon			Inhibitor	[1]
	Protein kinase C gamma			Inhibitor	[1]
	Protein kinase C theta			Inhibitor	[1]
	Protein kinase C zeta			Inhibitor	[1]
Ref 1	J Med Chem. 1992 Feb 7;35(3):573-83.Multivariate analysis by the minimum spanning tree method of the structural determinants of diphenylethylenes and triphenylacrylonitriles implicated in estrogen receptor binding, protein kinase C activity, and MCF7 cell proliferation. To Reference

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.

Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.