TTD Drug ID: DNC012885

Drug Information
Name	4-Naphthalen-1-yl-5-piperidin-4-yl-isoxazol-3-ol
Indication	Not Available			Experimental
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
InChI	1S/C18H18N2O2/c21-18-16(17(22-20-18)13-8-10-19-11-9-13)15-7-3-5-1 2-4-1-2-6-14(12)15/h1-7,13,19H,8-11H2,(H,20,21)
InChIKey	WDMOSRJVOUIQMD-UHFFFAOYSA-N
Canonical SMILES	C1CNCCC1C2=C(C(=O)NO2)C3=CC=CC4=CC=CC=C43
Target	GABA receptor alpha-1 subunit			Inhibitor	[1]
	GABA receptor alpha-2 subunit			Inhibitor	[1]
	GABA receptor beta-2 subunit			Inhibitor	[1]
	GABA receptor gamma-2 subunit			Inhibitor	[1]
Ref 1	J Med Chem. 2005 Jan 27;48(2):427-39.Potent 4-aryl- or 4-arylalkyl-substituted 3-isoxazolol GABA(A) antagonists: synthesis, pharmacology, and molecular modeling. To Reference

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