Therapeutic Targets Database
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TTD Drug ID: DNC013314

Drug Information
NameAMG-628
IndicationNot AvailableExperimental    
Structure

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InChI1S/C25H25FN6O2S/c1-16(18-6-8-19(26)9-7-18)31-10-12-32(13-11-31)22
-14-23(28-15-27-22)34-20-4-3-5-21-24(20)30-25(35-21)29-17(2)33/h3
-9,14-16H,10-13H2,1-2H3,(H,29,30,33)/t16-/m1/s1
InChIKeyQUHZTEMPQQZPNB-MRXNPFEDSA-N
Canonical SMILESCC(C1=CC=C(C=C1)F)N2CCN(CC2)C3=CC(=NC=N3)OC4=C5C(=CC=C4)SC(=N5)NC(=O)C    
Isomeric SMILESC[C@H](C1=CC=C(C=C1)F)N2CCN(CC2)C3=CC(=NC=N3)OC4=C5C(=CC=C4)SC(=N5)NC(=
O)C
TargetVanilloid receptorInhibitor[1]
Vanilloid receptorInhibitor[1]
Ref 1J Med Chem. 2007 Jul 26;50(15):3528-39. Epub 2007 Jun 22.Novel vanilloid receptor-1 antagonists: 3. The identification of a second-generation clinical candidate with improved physicochemical and pharmacokinetic properties. To Reference



 

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