Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNCL002367

Drug Information
NameAMG 900
CompanyAmgen Thousand Oaks, CA
IndicationHematological malignancies (see also solid tumors)
[ICD9: 140-199, 140-239, 200-209, 210-229   ICD10: C00-C75, C00-C96, C7A, C7B, C81-C96, D10-D36, D3A]
Phase I    
Solid Tumors
[ICD9: 140-199, 210-229   ICD10: C00-C75, C7A, C7B, D10-D36, D3A]
Phase I    
Various cancer types
[ICD9: 140-239   ICD10: C00-C96]
Phase I    
Structure

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InChI1S/C28H21N7OS/c1-17-15-24(37-16-17)25-20-5-2-3-6-21(20)26(35-34-2
5)32-18-8-10-19(11-9-18)36-27-22(7-4-13-30-27)23-12-14-31-28(29)3
3-23/h2-16H,1H3,(H,32,35)(H2,29,31,33)
InChIKeyIVUGFMLRJOCGAS-UHFFFAOYSA-N
Canonical SMILESCC1=CSC(=C1)C2=NN=C(C3=CC=CC=C32)NC4=CC=C(C=C4)OC5=C(C=CC=N5)C6=NC(=NC=
C6)N    
FormulaC28H21N7OS
PubChem Compound IDCID 24856041.
TargetAurora
Aurora A Kinase
Aurora B Kinase
Aurora C Kinase



 

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