Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DNCL002550

Drug Information
NameIbrutinib
SynonymsPCI-32765
CompanyJanssen Biotech Horsham, PA Pharmacyclics Sunnyvale, CA
IndicationCLL (Fast Track) (see also lymphoma, myeloma)
[ICD9: 202.8, 203.0, 204.1   ICD10: C81-C96, C90.0, C91.1]
Phase III    
CLL (see also lymphoma, multiple myeloma)
[ICD9: 202.8, 203.0, 204.1   ICD10: C81-C96, C90.0, C91.1]
Phase I/II    
Diffuse large B-cell lymphoma
[ICD9: 200.0   ICD10: C83.3]
Phase II    
Diffuse large B-cell lymphoma, mantle cell lymphoma (see also leukemia, multiple myeloma)
[ICD9: 200.0, 200.4, 202.8, 203.0, 208.9   ICD10: C81-C96, C83.3, C85.1, C85.7, C90.0, C91-C95]
Phase II    
Follicular lymphoma
[ICD9: 202.0   ICD10: C82]
Phase I    
Mantle cell lymphoma (see also leukemia, myeloma)
[ICD9: 200.4, 202.8, 203.0, 208.9   ICD10: C81-C96, C85.7, C90.0, C91-C95]
Phase III    
Multiple MyelomaPhase II    
Myeloma (see also leukemia, lymphoma)
[ICD9: 202.8, 203.0, 208.9   ICD10: C81-C96, C90.0, C91-C95]
Phase II    
Refractory/relapsed patients with Mantle Cell Lymphoma (single agent)
[ICD9: 200.4   ICD10: C85.7]
Phase III    
Relapsed/refractory patients with Chronic Lymphocytic Leukemia (in combination with Bendamustine and Rituximab)
[ICD9: 204.1   ICD10: C91.1]
Phase III    
Relapsed/refractory patients with Chronic Lymphocytic Leukemia (single agent)
[ICD9: 204.1   ICD10: C91.1]
Phase III    
Treatment nave patients with Chronic Lymphocytic Leukemia (single agent)
[ICD9: 204.1, 208.9   ICD10: C91-C95, C91.1]
Phase III    
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
InChI1S/C25H24N6O2/c1-2-21(32)30-14-6-7-18(15-30)31-25-22(24(26)27-16-
28-25)23(29-31)17-10-12-20(13-11-17)33-19-8-4-3-5-9-19/h2-5,8-13,
16,18H,1,6-7,14-15H2,(H2,26,27,28)/t18-/m1/s1
InChIKeyXYFPWWZEPKGCCK-GOSISDBHSA-N
Canonical SMILESC=CC(=O)N1CCCC(C1)N2C3=C(C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)C(=NC=N3)N    
Isomeric SMILESC=CC(=O)N1CCC[C@H](C1)N2C3=C(C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)C(=NC=N3)N
FormulaC25H24N6O2
PubChem Compound IDCID 24821094.



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543