Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Drug ID: DPR000046

Drug Information
NameFPL-14294
Synonyms4-(Sulfoxy)phenylacetyl-methionyl-glycyl-trptophyl-methionyl-aspartyl-methylphenylalaninehydrazide; L-Phenylalaninamide, N-((4-(sulfooxy)phenyl)acetyl)-L-methionylglycyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-nalpha-methyl-; 154132-95-3; Hpa(SO3H)-met-gly-trp-met-asp-mephe-NH2NH3; (3S)-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-[[2-[[(2S)-4-methylsulfanyl-2-[[2-(4-sulfooxyphenyl)acetyl]amino]butanoyl]amino]acetyl]amino]propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-[[(2S)-2-(methylamino)-3-phenylpropanoyl]amino]-4-oxobutanoic acid; AC1L31X9; CID132969; Fpl-14294; 4-(Sulfoxy)-phenylacetyl(mephe6)cck-6; Fpl 14294
CompanyFisons
IndicationObesity
[ICD9: 278   ICD10: E66]
Preclinical    [1]
Structure

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InChI1S/C45H56N8O13S3/c1-46-35(21-27-9-5-4-6-10-27)43(60)53-45(62)37(2
4-40(56)57)52-42(59)34(18-20-68-3)51-44(61)36(23-29-25-47-32-12-8
-7-11-31(29)32)50-39(55)26-48-41(58)33(17-19-67-2)49-38(54)22-28-
13-15-30(16-14-28)66-69(63,64)65/h4-16,25,33-37,46-47H,17-24,26H2
,1-3H3,(H,48,58)(H,49,54)(H,50,55)(H,51,61)(H,52,59)(H,56,57)(H,5
3,60,62)(H,63,64,65)/t33-,34-,35-,36-,37-/m0/s1
InChIKeyPKMRCHBERGHHNY-LTLCPEALSA-N
Canonical SMILESCNC(CC1=CC=CC=C1)C(=O)NC(=O)C(CC(=O)O)NC(=O)C(CCSC)NC(=O)C(CC2=CNC3=CC=
CC=C32)NC(=O)CNC(=O)C(CCSC)NC(=O)CC4=CC=C(C=C4)OS(=O)(=O)O    
Isomeric SMILESCN[C@@H](CC1=CC=CC=C1)C(=O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCSC)NC(=O)
[C@H](CC2=CNC3=CC=CC=C32)NC(=O)CNC(=O)[C@H](CCSC)NC(=O)CC4=CC=C(C=C4)OS
(=O)(=O)O
CAS NumberCAS 154132-95-3
PubChem Compound IDCID 132969.
PubChem Substance IDSID 709278.
TargetCholecystokinin receptor type AAgonist[1]
Ref 1Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60. To Reference



 

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