Therapeutic Targets Database
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TTD Drug ID: DPR000146

Drug Information
NameLY367265
SynonymsMolPort-003-947-263; Lopac0_000648; NCGC00015600-04; LY-367,265; CHEBI:713416; NCGC00015600-02; AC1NDRET; MLS002172448; Lopac-L-2411; L 2411; CID4605800; L020228; EU-0100648; SMR001254083; CHEMBL1079460; NCGC00015600-01; NCGC00094014-01; NCGC00094014-02; L2411_SIGMA; 1-[2-[4-(6-fluoro-1H-indol-3-yl)-3,6-dihydro-1(2H)-pyridinyl]ethyl]-5,6-dihydro-1H,4H-[1,2,5]thiadiazolo[4.3.2-ij]quinoline-2,2-dioxide
CompanyLilly
IndicationDepression
[ICD9: 311   ICD10: F32]
Discontinued    
Structure

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InChI1S/C24H25FN4O2S/c25-19-6-7-20-21(16-26-22(20)15-19)17-8-11-27(12-
9-17)13-14-28-23-5-1-3-18-4-2-10-29(24(18)23)32(28,30)31/h1,3,5-8
,15-16,26H,2,4,9-14H2
InChIKeyBJIPVHLRWSDKOS-UHFFFAOYSA-N
Canonical SMILESC1CC2=C3C(=CC=C2)N(S(=O)(=O)N3C1)CCN4CCC(=CC4)C5=CNC6=C5C=CC(=C6)F    
Therapeutic ClassPsychiatric
PubChem Compound IDCID 4605800.
PubChem Substance IDSID 6788488.
Target5-HT2A receptorInhibitor[1]
Norepinephrine transporterInhibitor[1]
Serotonin transporterInhibitor[1]
Ref 1Curr Top Med Chem. 2006;6(17):1801-23.Serotonin reuptake inhibitors: the corner stone in treatment of depression for half a century--a medicinal chemistry survey. To Reference



 

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