Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Target ID: TTDR00001

Target Information
NameAlpha-amylase    
Type of targetResearch target    
SynonymsAlpha-glucosidase    
DiseasePancreatic disease[1]
Target ValidationClick to Find Target Validation Information.    
Inhibitor4,6-Dideoxyglucose[2]
6-Deoxy-Alpha-D-Glucose[2]
Beta-D-Glucose[2]
DEOXYNOJIRIMYCIN[3]
Double Oxidized Cysteine[2]
Maltose[4]
Nicotinamide-Adenine-Dinucleotide[2]
Tendamistat[5]
Cross References 3D Structure
Related Literature
On-Line Medical Dictionary
Ref 1Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. To Reference
Ref 2Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. To Reference
Ref 3J Med Chem. 1994 Oct 28;37(22):3701-6.Nitrogen-in-the-ring pyranoses and furanoses: structural basis of inhibition of mammalian glycosidases. To Reference
Ref 4Nucleic Acids Res. 2011 January; 39(Database issue): D1035¨CD1041. DrugBank 3.0: a comprehensive resource for ¡®Omics¡¯ research on drugs To Reference
Ref 5Influence of Specific Signal Peptide Mutations on the Expression and Secretion of the alpha -Amylase Inhibitor Tendamistat in Streptomyces lividans. J Biol Chem. 1996 Jun 21;271(25):15244-52. To Reference



 

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