Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Target ID: TTDR00348

Target Information
NameNicotinate-nucleotide adenylyltransferase    
Type of targetResearch target    
SynonymsDeamido-NAD(+) diphosphorylase    
Deamido-NAD(+) pyrophosphorylase    
Deamido-NAD(+)Nicotinate-nucleotide adenylyltransferase pyrophosphorylase    
NaMN adenylyltransferase    
Nicotinate mononucleotide adenylyltransferase    
DiseaseBacterial infections
[ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104   ICD10: A00-A09, A15-A19, A20-A28, A30-A49, A65-A69, A70-A74, A75-A79]
EC NumberEC
UniProt IDP52085
PDB Structure1K4K; 1K4M.    
FunctionCatalyzes the reversible adenylation of nicotinate mononucleotide (namn) to nicotinic acid adenine dinucleotide (naad).    
Cross References 3D Structure
Related Literature
On-Line Medical Dictionary
Ref 1Crystal structures of E. coli nicotinate mononucleotide adenylyltransferase and its complex with deamido-NAD. Structure. 2002 Jan;10(1):69-79. To Reference
Ref 2Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. To Reference


Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.

Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543