Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Target ID: TTDR01157

Target Information
NameProbable nicotinate-nucleotide adenylyltransferase    
Type of targetResearch target    
SynonymsDeamido-NAD(+) diphosphorylase    
Deamido-NAD(+) pyrophosphorylase    
NaMN AT    
NaMN adenylyltransferase    
Nicotinate mononucleotide adenylyltransferase    
Nicotinate-nucleotide adenylyltransferase    
Nicotinic acid mononucleotide adenylyltransferase    
DiseaseBacterial infections
[ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104   ICD10: A00-A09, A15-A19, A20-A28, A30-A49, A65-A69, A70-A74, A75-A79]
BioChemical ClassTransferases transferring phosphorus-containing groups    
EC NumberEC
PathwayMetabolic pathways
Nicotinate and nicotinamide metabolism
UniProt IDQ9HX21
PDB Structure1YUL; 1YUM; 1YUN.    
FunctionCatalyzes the reversible adenylation of nicotinate mononucleotide (namn) to nicotinic acid adenine dinucleotide (naad) (by similarity).    
Cross References 3D Structure
Related Literature
On-Line Medical Dictionary
Ref 1Crystallization and preliminary X-ray crystallographic analysis of nicotinic acid mononucleotide adenylyltransferase from Pseudomonas aeruginosa. Acta Crystallogr D Biol Crystallogr. 2004 May;60(Pt 5):948-9. Epub 2004 Apr 21. To Reference
Ref 2Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. To Reference


Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.

Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543