Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Target ID: TTDR01163

Target Information
NameGABA transporter-3    
Type of targetResearch target    
SynonymsGABA transporter 3    
GABA transporter type 3    
Gamma-aminobutyric acid transporter 3    
DiseaseNeurological diseases[1]
Target ValidationClick to Find Target Validation Information.    
Inhibitor2,4-Diamino-butyric acid (GABA)[2]
4-Hydroxy-piperidine-3-carboxylic acid[3]
Cross References 3D Structure
Related Literature
On-Line Medical Dictionary
Ref 1Stable expression of a neuronal gamma-aminobutyric acid transporter, GAT-3, in mammalian cells demonstrates unique pharmacological properties and ion dependence. Mol Pharmacol. 1994 Sep;46(3):550-7. To Reference
Ref 2J Med Chem. 1986 Feb;29(2):224-9.Glycine antagonists. Synthesis, structure, and biological effects of some bicyclic 5-isoxazolol zwitterions. To Reference
Ref 3J Med Chem. 1982 Oct;25(10):1157-62.Hydroxy- and amino-substituted piperidinecarboxylic acids as gamma-aminobutyric acid agonists and uptake inhibitors. To Reference
Ref 4J Med Chem. 1981 Jul;24(7):788-94.Epimeric cis-decahydroquinoline-5-carboxylic acids: effects on gamma-aminobutyric acid uptake and receptor binding in vitro. To Reference


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