Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
   

 

TTD Target ID: TTDR01375

Target Information
NamemRNA of PKA Catalytic Subunit C-alpha    
Type of targetResearch target    
DiseaseNot Available
UniProt IDP17612
PDB Structure2GU8; 3AGL; 3AGM; 3AMA; 3AMB; 3L9L; 3L9M; 3L9N; 3MVJ; 3NX8; 3OOG; 3OVV; 3OWP; 3OXT; 3P0M; 3POO; 3VQH; 4AE6; 4AE9.    
Target ValidationClick to Find Target Validation Information.    
Inhibitor4-[ (3,5-diamino-1H-pyrazol-4-yl)diazenyl]phenol[1]
BALANOL[2]
NM-PP1[3]
Ro-4396686[4]
AntisenseISIS 102450[5]
ISIS 102454[5]
ISIS 102458[5]
ISIS 102462[5]
ISIS 102466[5]
ISIS 102478[5]
ISIS 102482[5]
ISIS 102486[5]
ISIS 102490[5]
ISIS 102558[5]
ISIS 102563[5]
ISIS 102584[5]
ISIS 102599[5]
ISIS 102604[5]
ISIS 102609[5]
ISIS 102614[5]
ISIS 102619[5]
ISIS 102624[5]
ISIS 102629[5]
ISIS 102633[5]
ISIS 102660[5]
ISIS 102664[5]
ISIS 102668[5]
ISIS 102676[5]
Cross References 3D Structure
Related Literature
On-Line Medical Dictionary
Ref 1J Med Chem. 2006 Nov 2;49(22):6500-9.4-arylazo-3,5-diamino-1H-pyrazole CDK inhibitors: SAR study, crystal structure in complex with CDK2, selectivity, and cellular effects. To Reference
Ref 2J Med Chem. 2005 Sep 8;48(18):5613-38.Joys of molecules. 2. Endeavors in chemical biology and medicinal chemistry. To Reference
Ref 3Biochem J. 2007 Dec 15;408(3):297-315.The selectivity of protein kinase inhibitors: a further update. To Reference
Ref 4Bioorg Med Chem Lett. 2006 Apr 1;16(7):1950-3. Epub 2006 Feb 3.Biological evaluation of a multi-targeted small molecule inhibitor of tumor-induced angiogenesis. To Reference
Ref 5US Patent 6248586 To Reference



 

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National University of Singapore, Singapore


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