Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Target ID: TTDS00349

Target Information
NameNicotinic acetylcholine receptor alpha subunit    
Type of targetSuccessful target    
DiseaseMuscle contraction[1]
Drug(s)DoxacuriumApprovedSpasms, Pain[2]
BioChemical ClassIon transport    
Cross References 3D Structure
Related Literature
On-Line Medical Dictionary
Ref 1Characterization of the muscarinic receptor subtype(s) mediating contraction of the guinea-pig lung strip and inhibition of acetylcholine release in the guinea-pig trachea with the selective muscarinic receptor antagonist tripitramine. Br J Pharmacol. 1997 Sep;122(1):133-41. To Reference
Ref 2Interaction of nondepolarizing muscle relaxants with M2 and M3 muscarinic receptors in guinea pig lung and heart. Anesthesiology. 1996 Jan;84(1):155-61. To Reference


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