Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

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Search results in terms of drug list:

Search results in terms of target list:

Examples: Oseltamivir; Alzheimer's disease; MAPK pathway; Muscarinic acetylcholine receptor ...
Read more about TTD Query Methods

 

NEWS

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TTD Version 4.3.02 release on Aug 25th 2011. New version of TTD provides Quantitative Structure-Activity Relationship (QSAR) models and Target Validation Information for TTD drug target. Moreover, Multi Target Agents Data with structure and potency information, Drug Combinations and Nature-derived Drugs together with drug species origin data are also included.
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Therapeutic Target Database

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A database to provide information about the known and explored therapeutic protein and nucleic acid targets, the targeted disease, pathway information and the corresponding drugs directed at each of these targets. Also included in this database are links to relevant databases containing information about target function, sequence, 3D structure, ligand binding properties, enzyme nomenclature and drug structure, therapeutic class, clinical development status. All information provided are fully referenced.
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Statistics of this database

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This database currently contains 2,025 targets, including 364 successful, 286 clinical trial, 44 discontinued and 1,331 research targets, 17,816 drugs, including 1,540 approved, 1,423 clinical trial, 14,853 experimental drugs and 3,681 multi-target agents (14,170 small molecules and 652 antisense drugs with available strucuture or oligonucleotide sequence). Targets and drugs in this database cover 61 protein biochemical class and 140 drug therapeutic classes respectively.
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How to cite our database

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Zhu F, Shi Z, Qin C, Tao L, Liu X, Xu F, Zhang L, Song Y, Liu XH, Zhang JX, Han BC, Zhang P, Chen YZ. Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery. Nucleic Acids Res. 40(D1): D1128-1136, 2012. PubMed.

Chen X, Ji ZL, Chen YZ. TTD: Therapeutic Target Database. Nucleic Acids Res. 30(1):412-415, 2002. PubMed

Zhu F, Han BC, Pankaj Kumar, Liu XH, Ma XH, Wei XN, Huang L, Guo YF, Han LY, Zheng CJ, Chen YZ. Update of TTD: Therapeutic Target Database. Nucleic Acids Res. 38(suppl 1):D787-91, 2010. PubMed

Last update by

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Aug 25th, 2011
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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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