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TTD Drug ID: DAP000040

Drug Information
NameVerapamil    
SynonymsHMS1791L15; 2-(3,4-Dimethoxyphenyl)-5-((2-(3,4-dimethoxyphenyl)ethyl)(methyl)amino)-2-isopropylpentanenitrile, (+/-)-; 5-[(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile; NCI60_020143; Spectrum2_001740; nchembio.79-comp5; Isoptimo; nchembio.368-comp2; 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile; LS-174; Verapamilum; Verapamilo; Cordilox; (+/-)-VERAPAMIL; Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino) propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-; 52-53-9; KBio3_000465; KBio2_002801; 2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-(1-methylethyl) pentanenitrile; Valeronitrile, 5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropyl-; Verapamil [USAN:INN:BAN]; C27H38N2O4; CP-16533-1; NINDS_000399; D02356; KBio2_000233; Dilacoran; KBioGR_000233; NCGC00024710-04; Benzeneacetonitrile, .alpha.-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-.alpha.-(1-methylethyl)-; CHEBI:9948; Verapamil (USAN/INN); BRD-A09533288-003-05-6; Veracim; KBio2_007479; CID2520; NSC272366; Verapamilum [INN-Latin]; Isoptin; Prestwick3_000141; KBioSS_000233; Iproveratril; L001330; HMS2089H17; Bio1_001403; Bio2_000713; alpha-(3-((2-(3,4-Dimethoxyphenyl)ethyl)-methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)benzeneacetonitrile; DivK1c_000399; KBio2_002343; AB00053495; Verapamil [USAN:BAN:INN]; Prestwick1_000141; Veraptin; alpha-((N-Methyl-N-homoveratryl)-gamma-aminopropyl)-3,4-dimethoxyphenylacetonitrile; 5-((3,4-Dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile; Bio-0754; NCGC00024710-07; Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-, (+-)-; CCRIS 6749; BPBio1_000268; Isotopin; KBio2_005369; Calcan; I06-0063; NCGC00016083-14; Calan; UNII-CJ0O37KU29; Verexamil; MolPort-000-721-258; KBioGR_001372; CHEMBL6966; NCGC00024710-05; BRD-A09533288-001-02-7; SPBio_001820; SPBio_002181; HMS1989L15; D-365; EINECS 200-145-1; Prestwick2_000141; DB00661; Verapamilo [INN-Spanish]; 56949-77-0; KBioGR_002343; 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile; cMAP_000023; Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-; STK538085; KBio2_004911; FT-0080127; (1)-3-(3,4-Dimethoxyphenyl)-6-((5,6-dimethoxyphenethyl)methylamino)hexane-3-carbonitrile; NCGC00024710-08; BSPBio_001513; Prestwick0_000141; IDI1_033983; KBioSS_002346; Spectrum5_001786; KBio1_000399; C07188; EINECS 260-462-6; Spectrum4_000906; Vasolan; KBio3_002823; IDI1_000399; AC-16016; AC1L1DV5; BSPBio_002358; Lopac0_001237; (+-)-Verapamil; KBio3_000466; Drosteakard; NCGC00024710-09; NCGC00024710-06; Arpamyl; Dexverapamil; alpha-Isopropyl-alpha-((N-methyl-N-homoveratryl)-gamma-aminopropyl)-3,4-dimethoxyphenylacetonitrile; BSPBio_000242; Bio1_000914; VERAPAMIL; Bio2_000233; Bio1_000425    
Trade NameIsoptin; Verelan; Calan; Bosoptin; Covera-HS    
CompanyPfizer Inc    
IndicationHypertension and anginaApproved    [1]
Structure

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Click to save drug structure in 2D MOL format
   
Therapeutic ClassAnalgesics    
CAS NumberCAS 52-53-9
FormularC27H38N2O4    
PubChem Compound IDCID 2520.    
PubChem Substance IDSID 9397.    
ChEBI9948;    
SuperDrug ATC IDC08DA01;    
SuperDrug CAS ID000052539;    
TargetVoltage-dependent T-type calcium channelBlocker[2][3]
Ref 1Partial restoration of mutant enzyme homeostasis in three distinct lysosomal storage disease cell lines by altering calcium homeostasis. PLoS Biol. 2008 Feb;6(2):e26. To Reference
Ref 2Mechanism of tissue-selective drug action in the cardiovascular system. Mol Interv. 2005 Apr;5(2):84-93. To Reference
Ref 3Combination therapy and target organ protection in hypertension and diabetes mellitus. Am J Hypertens. 1997 Sep;10(9 Pt 2):198S-201S. To Reference



 

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