Therapeutic Targets Database
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TTD Drug ID: DAP000058

Drug Information
NameTerlipressin    
SynonymsHS-2028; Terlipressine [INN-French]; (2s)-1-{[(4r,7s,10s,13s,16s,19r)-19-{[({[(aminoacetyl)amino]acetyl}amino)acetyl]amino}-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-n-{(2s)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl}pyrrolidine-2-carboxamide(non-preferred name); EINECS 238-680-8; Terlipressinum [INN-Latin]; Terlipressina [INN-Spanish]; AC1Q5JB2; UNII-7Z5X49W53P; Terlipressine; Terlipressin [BAN:INN]; DB02638; Terlipressina; Terlipressin; AC1L2HDP; 14636-12-5; N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin; glypressin; (2S)-1-[(4R,7S,10S,13S,16S,19R)-19-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]pyrrolidine-2-carboxamide; LS-161411; CID72081; Lucassin; Terlipressinum    
Trade NameGlypressin    
CompanyFerring Pharmaceuticals    
IndicationHypertensionApproved    [1]
Structure

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Therapeutic ClassVasoconstrictor Agents    
CAS NumberCAS 14636-12-5
FormularC52H74N16O15S2    
PubChem Compound IDCID 72081.    
PubChem Substance IDSID 214342.    
SuperDrug ATC IDH01BA04;    
SuperDrug CAS ID014636125;    
TargetVasopressin V1a receptorStimulator[2]
Ref 1Pharmacology, clinical efficacy and safety of terlipressin in esophageal varices bleeding, septic shock and hepatorenal syndrome. Expert Rev Gastroenterol Hepatol. 2007 Dec;1(2):207-17. To Reference
Ref 2Investigational vasopressin receptor modulators in the pipeline. Expert Opin Investig Drugs. 2009 Aug;18(8):1119-31. To Reference



 

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